Tag: drug development

Biomarkers in early drug development

The EMA glossary defines a biological marker, or biomarker, as ‘an objective and quantifiable measure of a physiological process, pathological process or response to a treatment (excluding measurements of how an individual feels or functions)’. Similarly, the FDA defines a biomarker as ‘a defined characteristic that is measured as an indicator of normal biological processes, continue reading…

Evaluation of drug safety does not start at candidate nomination: Create value by de-risking early

Picture of Ruud Bueters

  Drug development is a daunting and difficult task where all the puzzle pieces need to click to result in an efficacious and safe treatment for patients. It is a high-risk endeavor involving many different scientific and non-scientific disciplines over a long period of time. The current estimates to develop a drug are about 2.3 continue reading…

Unleashing the Power of Drug Repurposing

Drug repurposing, also called drug repositioning, reprofiling or retasking, is the process of identifying a new use for an existing medicine/active substance outside the scope of the original indication(s). It includes new therapeutic uses for existing medicines, different formulations of the same medicine, and/or creating new combinations of medicines or medicines with medical devices[1]. Drug continue reading…

Inez de Greef elected to the NAE

NAE fellows 2023

Inez de Greef elected as fellow of the Netherlands Academy of Engineering We are thrilled to announce that Inez de Greef, CEO of Treeway and co-founder and Managing Partner of 3D-PharmXchange, has been elected as a fellow of the Netherlands Academy of Engineering (NAE). The NAE brings together top experts in technological sciences and applied continue reading…